On October 22, the Nationals stole Game 1 of the World Series 5-4 and took home field advantage from the Astros. The Astros had home-field advantage so the game was at Minute Maid Park in Houston.

The Astros pitched Cole who is an AL Cy Young candidate. The Nationals pitched Max Scherzer who is a former Cy Young winner.

The Astros started off hot and scored two runs on a Gurriel double in the first inning. The Nationals then came back with two solo home runs, one in the second and one in the fourth inning.

With the score tied 2-2, the Nationals came out hot in the fifth inning. Suzuki started the inning off with a walk, followed by a single from Robles. Then Turner lined out, but the next batter, Eaton, singled to right and scored Suzuki. Two batters later, with two outs, Soto doubled to deep left field and scored two runs.

The score was now 5-2 and the Astros were forced to take their star pitcher out of the game. Until the seventh inning the pitching was taking over the game.

In the seventh, Springer led off with a solo home run. The Nationals were still on top 5-3. Then, in the eighth, Springer had a double which scored another run for the Astros.

In the bottom of the ninth, Doolittle came in to pitch. He closed out the game 1, 2, 3.